Can I give vesicants via a midline catheter?

Created by Faye Team, Modified on Wed, 03 Jan 2024 at 10:45 AM by Jaime Weimer

A midline catheter is a peripheral IV catheter because the tip does not terminate in the central circulation, but rather in the axillary vein of the upper arm. The infusion of IV push or intermittent vesicant infusions via a midline catheter is controversial because there is potential for an undetected extravasation where the tip terminates. The use of a midline catheter is contraindicated for continuous irritant or vesicant therapy or solutions with extremes of pH or osmolality.


Cope, D.G. (2023). Midline catheters. In C. Backler and J. Kirmse (Eds)., Access device guidelines: Recommendations for nursing practice and education (4th ed., pp. 25-31). Oncology Nursing Society.

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